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目的应用定量组织速度成像(QTVI)技术探讨不同左室构型高血压患者颈动脉重构的超声特征。方法入选大连大学附属中山医院门诊健康体检者及门诊或住院的高血压患者。对照组35例,其中男18例,女17例,年龄(56.3±14.8)岁。高血压病组99例,其中,左室正常构型(LVN)组32例,男17例,女15例,年龄(59.6±13.5)岁;左室向心性重构(LVR)组32例,男17例,女15例,年龄(57.0±14.5)岁;左心室肥厚(LVH)组35例,男17例,女18例,年龄(60.5±12.6)岁。应用二维及QTVI技术,分别检测对照组及高血压病各组受试者的颈动脉的二维及组织多普勒相关参数。结果与对照组比较,高血压病组的经颈总动脉直径和脉压校正后的颈总动脉后壁峰值速度(Vimax)及加速度(Aci)均明显减低(均P<0.05),且LVN、LVR、LVH组测值依次减低,其组间比较差异有统计学意义(均P<0.05);高血压病组的经心率和脉压校正后的颈总动脉后壁加速时间(Ati)及减速时间(Dti)均明显缩短,且LVN、LVR、LVH组测值依次缩短,其组间比较差异有统计学意义(均P<0.05)。结论应用QTVI技术能够评价不同左室构型高血压患者颈动脉的功能重构特征。
Objective To investigate the ultrasound features of carotid artery remodeling in patients with different left ventricular hypertrophy using quantitative tissue velocity imaging (QTVI). Methods Selected Zhongshan Hospital outpatient health examination and outpatient or inpatient hypertensive patients. The control group of 35 patients, including 18 males and 17 females, aged (56.3 ± 14.8) years. There were 99 cases of hypertensive patients, including 32 cases of normal left ventricular (LVN) group, 17 males and 15 females, with a mean age of 59.6 ± 13.5 years; 32 cases of left ventricular concentric remodeling (LVR) There were 17 males and 15 females, with a mean age of 57.0 ± 14.5 years old. There were 35 cases of left ventricular hypertrophy (LVH), 17 males and 18 females, with a mean age of (60.5 ± 12.6) years. Two-dimensional and QTVI techniques were used to detect the two-dimensional and tissue Doppler parameters of the carotid arteries of control subjects and hypertensive subjects respectively. Results Compared with the control group, the mean carotid artery diameter and the corrected carotid artery posterior wall velocity (Vimax) and acceleration (Aci) in hypertensive patients were significantly decreased (all P <0.05) LVR and LVH decreased in turn, with significant difference between the two groups (all P <0.05). The heart rate and pulse-pressure-corrected carotid artery posterior wall acceleration time (Ati) Time (Dti) were significantly shortened, and LVN, LVR, LVH group measured values shortened in turn, the difference between the groups was statistically significant (P <0.05). Conclusion QTVI can be used to evaluate the carotid artery remodeling in patients with different LVHs.