急性坏死性胰腺炎(ANP)约占急性胰腺炎的20%[1],其病情凶险、并发症多、病死率高(19%~24%)[2],可分为早期的急性反应期、中期的全身感染期及后期的残余感染期,ARDS、急性肾功能衰竭、脑病、休克、全身细菌感染、深部霉菌感染、胰瘘、肠瘘、胃瘘等是死亡的主要原因。为探讨ANP并 Acute necrotizing pancreatitis (ANP) accounts for about 20% of acute pancreatitis [1], its dangerous condition, multiple complications, high mortality (19% to 24%) [2], can be divided into early acute reaction , Middle stage of systemic infection and the later period of infection, ARDS, acute renal failure, encephalopathy, shock, systemic bacterial infection, deep mold infection, pancreatic fistula, intestinal fistula, gastric fistula are the main causes of death. To explore ANP and