制备人体单克隆抗体,即体外诱导产生一个预知抗原的抗体的障碍之一将很快被克服。日内瓦大学的Jeffery Van Ness和Ulrich Laemmli与美国科罗拉多大学的David Pettijohn一道创造了一种使用产生弱免疫的不溶性蛋白质体外免疫小鼠脾细胞的方法,以诱导对这种 One of the obstacles to producing human monoclonal antibodies, that is, antibodies that in vitro induce the production of a pre-identified antigen, will soon be overcome. Jeffery Van Ness and Ulrich Laemmli of the University of Geneva, in collaboration with David Pettijohn of the University of Colorado, have created a method of immunizing mouse splenocytes in vitro using insoluble proteins that produce weak immunity to induce this