论文部分内容阅读
采用免疫组化SP法对 30例子宫内膜癌组织中的P1 6蛋白进行检测 ,探讨P1 6蛋白在子宫内膜癌组织及癌旁正常组织中表达的意义。结果显示 :30例宫内膜癌组织中P1 6蛋白表达率为 50 .0 0 % ,低于癌旁正常宫内膜组织的 1 0 0 .0 0 % (P <0 .0 1 )。高分化癌P1 6蛋白表达高于中、低分化癌 (P <0 .0 1 )。结果表明 :P1 6蛋白表达与宫内膜癌发生及分化有关
The immunohistochemical SP method was used to detect the P1 6 protein in 30 cases of endometrial carcinoma and to explore the significance of P1 6 protein expression in endometrial carcinoma and adjacent normal tissues. The results showed that the expression of P1 6 protein in 30 cases of endometrial carcinoma was 50.0%, which was lower than that of normal endometrial tissue adjacent to the tumor (100.0%, P0.01). The expression of P1 6 protein in well-differentiated carcinoma was higher than that in moderately differentiated carcinoma (P <0.01). The results showed that: P1 6 protein expression and the occurrence and differentiation of endometrial cancer