胃十二指肠溃疡病的流行病学 现今资料表明,约5％～10％的人在其一生中至少患过一次消化性溃疡。每年的新发病率约15～30/1000。近40年来在西方工业国家中胃十二指肠溃疡病的发病率和死亡率呈持续下降趋势,同时择期手术和急诊手术亦减少。直到70年代中期溃疡病死亡率的下降主要是因为生活水平的下降和对某些风险因素的暴露出现了改变,例如营养,抽烟或幽门螺杆菌。最近20年来H_2受体阻滞剂的使用也 Epidemiology of Gastroduodenal Ulcer Disease Current data show that about 5% to 10% of people have had at least one peptic ulcer in their lifetime. The annual new incidence is about 15 to 30/1000. In the past 40 years, the incidence and mortality of gastroduodenal ulcer disease in western industrial countries showed a continuous downward trend, while elective surgery and emergency surgery also decreased. The decline in mortality from ulcer disease until the mid-1970s was mainly due to a decline in living standards and exposure to certain risk factors such as nutrition, smoking, or Helicobacter pylori. The use of H 2 blockers for the last 20 years is also