舒必利(Sulpiride)1967年由法国首先合成。1974年上海第六制药厂仿制,先应用于治疗胃和十二指肠溃疡,次年始用于治疗精神病,发现有其独特的临床作用,并因其化学结构、药理作用和临床效能都与过去的抗精神病药不同,归类和命名很不一致,有“解除抑制剂”、“抗孤独剂”、“情绪兴奋剂”和“关系调节药物”等名称。 化学结构和性状:N—〔(乙基—1—吡咯烷基—2)甲基)〕甲氧—2氨磺酰—5—苯酰胺。是 Sulpiride was first synthesized by France in 1967. 1974 Shanghai Sixth Pharmaceutical Factory imitation, first applied to the treatment of gastric and duodenal ulcer, the following year is used to treat mental illness, found to have its unique clinical role, and because of its chemical structure, pharmacological effects and clinical efficacy with the past Of the different antipsychotics, classification and nomenclature is very inconsistent with the “anti-depressant”, “anti-lonely agent”, “emotional stimulants” and “relationship regulation drugs” and other names. Chemical Structure and Properties: N - [(Ethyl-1-pyrrolidinyl-2) methyl)] methoxy-2sulfamoyl-5-benzamide. Yes