论文部分内容阅读
晚近,各种医药学文献、杂志对维生素C(以下简称Vc)的评价甚多,Vc的用途不仅仅用于防治坏血病,还可以用于治疗急慢性感染,防治感冒,降低胆固醇,防治肿瘤及治疗肝胆疾病等等。本文仅就临床用药中维生素C与其他药物配伍应用产生的相互作用,归纳如下: 一、维生素C与抗生素类药物的相互作用: 1.Vc与氨苄青霉素同瓶静滴,可使混合后的溶液pH降低,导致氨苄青霉素失活。2.Vc与红霉素糖衣片或粉剂配伍后,因为Vc为一酸性物质,可使红霉素的甙键水解而失去抗菌作用。
Recently, a variety of medical literature, magazines on the vitamin C (hereinafter referred to as Vc) evaluation, Vc use not only for the prevention and treatment of scurvy, but also for the treatment of acute and chronic infections, prevention and treatment of colds, lowering cholesterol, prevention and treatment Tumor and hepatobiliary disease and so on. This article only on the clinical use of vitamin C and other drug compatibility applications arising from the interaction, summarized as follows: First, the interaction of vitamin C and antibiotics: 1.Vc with ampicillin bottle with intravenous infusion, the mixed solution Decreased pH leads to inactivation of ampicillin. 2.Vc and erythromycin sugar-coated tablets or powder compatibility, because Vc is an acidic substance, can make erythromycin glycosidic bond hydrolysis and loss of antibacterial effect.