通过硅胶和MCI柱色谱及制备液相色谱等分离方法从贵州道地药材金钗石斛茎中分离纯化得到7个联苄类化合物,经质谱和核磁共振等波谱技术将其结构分别鉴定为4,α-二羟基-3,5,3’-三甲氧基联苄(1)、4,5-二羟基-3,3’,α-三甲氧基联苄(2)、4,4’-二羟基-3,5,3’-三甲氧基联苄(3)、4,5-二羟基-3,3’-二甲氧基联苄(4)、4,3’-二羟基-3,5-二甲氧基联苄(5)、5,4’-二羟基-3,3’-二甲氧基联苄(6)和5,3’-二羟基-3-甲氧基联苄(7)。化合物1为新的联苄类化合物,化合物4为首次从该植物中分离得到。 Seven dibenzyl compounds were isolated and purified from the stems of Dendrobium nobile Lindl, Guizhou Medicinal Materials by silica gel, MCI column chromatography and preparative liquid chromatography. Their structures were identified as 4 by mass spectrometry and 1H NMR, respectively. (1), 4,5-dihydroxy-3,3 ’, α-trimethoxybibenzyl (2), 4,4’-bis Trimethoxybibenzyl (3), 4,5-dihydroxy-3,3’-dimethoxybibenzyl (4), 4,3’-dihydroxy-3, Dimethoxybibenzyl (5), 5,4’-dihydroxy-3,3’-dimethoxybibenzyl (6) and 5,3’-dihydroxy-3-methoxybibenzyl (7). Compound 1 is a novel bibenzyl compound, and compound 4 is isolated from this plant for the first time.