阴道是恶性滋养细胞肿瘤常见的转移部位,仅次于肺,占第二位。阴道转移瘤一般随着5——氟脲嘧啶(5—Fu)、更生霉素(K、S、M)全身化疗而治愈,然而有些病例却效果不佳,甚至完全无效。1981年我们遇到一例绒癌合并肺及阴道转移的病例,用5—Fu及KSM全身化疗6个疗程后,肺转移灶消失,但阴道转移瘤却越来越发展,加用5—Fu瘤体注射2疗程也无效,后改用氨甲喋呤(MTX)、更生霉素 Vagina is a common metastatic site of malignant trophoblastic tumor, second only to the lung, accounting for the second place. Vaginal metastases generally cure with systemic chemotherapy of 5-fluorouracil (5-Fu), dactinomycin (K, S, M), while others are ineffective or even completely ineffective. In 1981, we encountered a case of choriocarcinoma associated with lung and vaginal metastasis, with 5-Fu and KSM systemic chemotherapy after 6 courses of treatment, the lung metastases disappeared, but the vaginal metastases are more and more development, plus 5-Fu tumors Body injection 2 treatment is also invalid, after the switch to methotrexate (MTX), dactinomycin