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目的:探讨国产阿卡波糖片(卡博平)治疗2型糖尿病的疗效及安全性。方法:将2012年8月至2013年8月开平市第二人民医院收治的40例2型糖尿病患者随机分为观察组(国产阿卡波糖卡博平,20例)和对照组(进口阿卡波糖卡拜唐苹,20例),治疗8周后,观察两组空腹及餐后2 h血糖、糖化血红蛋白、TG、TC、HDL-C、等指标。结果:治疗8周后,两组空腹及餐后血糖、HbA1c较治疗前均明显下降,治疗前后比较,差异有统计学意义(P<0.05),但两组比较,差异无统计学意义(P>0.05)。与治疗前相比,两组治疗8周后TG、TC、HDL-C等比较,差异均无统计学意义(P>0.05)。两组不良反应比较,差异无统计学意义(P>0.05)。结论:国产阿卡波糖片卡博平是一种有效的口服抗高血糖药物,具有与拜唐苹相近的有效性和安全性。
Objective: To investigate the efficacy and safety of domestic acarbose (carbopol) in the treatment of type 2 diabetes mellitus. Methods: Forty patients with type 2 diabetes admitted to the Second People’s Hospital of Kaiping City from August 2012 to August 2013 were randomly divided into observation group (domestic acarbose carbopine, 20 cases) and control group (imported After treatment for 8 weeks, two groups of fasting and postprandial 2 h blood glucose, glycosylated hemoglobin, TG, TC, HDL-C, and other indicators were observed. Results: After 8 weeks of treatment, the fasting and postprandial blood glucose and HbA1c in both groups were significantly lower than those before treatment (P <0.05), but there was no significant difference between the two groups (P > 0.05). Compared with before treatment, TG, TC, HDL-C and other two groups after 8 weeks of treatment, the difference was not statistically significant (P> 0.05). Adverse reactions between the two groups, the difference was not statistically significant (P> 0.05). Conclusion: The domestic acarbose carboprofen is an effective oral anti-hyperglycemic drug with Baitang Ping similar efficacy and safety.