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目的探讨罗红霉素和地塞米松尿道灌注治疗沙眼衣原体(CT)和(或)解脲脲原体(UU)性尿道炎的疗效。方法筛选出120例不并发淋病、附睾炎及前列腺炎,有尿道炎症状,尿道分泌物萤光聚合酶链反应检查CT和(或)UU阳性患者,随机分为两组,每组各60例。服药组,口服罗红霉素;灌注组,用1%罗红霉素和0.5%地塞米松作尿道灌注。10d为1个疗程。结果经过1～2个疗程治疗,服药组治愈34例,好转8例,无效18例;灌注组治愈49例,好转6例,无效5例。结论尿道灌注治疗明显优于口服药物治疗,且无明显不良反应。
Objective To investigate the efficacy of roxithromycin and dexamethasone urethral perfusion in the treatment of Chlamydia trachomatis (CT) and / or Ureaplasma urealyticum (UU) urethritis. Methods A total of 120 patients with non-concurrent gonorrhea, epididymitis and prostatitis were screened for the presence of urethritis and CT and / or UU positive by fluorescence polymerase chain reaction of urethral secretions. The patients were randomly divided into two groups, 60 cases in each group . The medication group, oral roxithromycin; perfusion group, with 1% roxithromycin and 0.5% dexamethasone for urethral perfusion. 10d for a course of treatment. Results After 1 to 2 courses of treatment, the medication group cured 34 cases, 8 cases improved, 18 cases ineffective; perfusion group cured 49 cases, 6 cases improved, 5 cases ineffective. Conclusions The urethral perfusion therapy is obviously better than oral medication, and no obvious adverse reactions.