Dear Colleagues,rnDespite 2021 is a year full of challenges and continued to be so, it has been a busy and encouraging year for Neural Regeneration Research (NRR)! Since 2020 with the new impact factor reached 3.171, NRR became top 50％ of neuroscience journals (JCR Q2, among 271 journals under the specialty “Neurosciences”). In the past year, NRR has made great progress, especially in internationalization and the scientific level, and has the strength to compete with recognized journals in the same field.