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目的 探讨碘酊烧灼联合机械刮除角膜上皮行角膜全结膜遮盖手术的效果。方法 对实验组 2 0只纯种新西兰大耳白兔分组进行单纯机械刮除角膜上皮 (单纯法 )及碘酊烧灼联合机械刮除角膜上皮 (综合法 )角膜全结膜瓣遮盖术。结果 单纯法 10只眼 ,3眼结膜与角膜愈着 ,手术成功 ,7眼未成功。综合法 10眼 ,8眼手术成功 ,2眼未成功。 2组成功率有显著差异 (P<0 .0 5 )。结论 综合法能更有效的毁损角膜上皮及角膜干细胞 ,提高手术成功率。
Objective To investigate the effect of iodine tincture cauterization combined with mechanical curettage of corneal whole conjunctiva. Methods A total of 20 New Zealand white rabbits in experimental group were divided into two groups: simple mechanical scraping of corneal epithelium (simple method) and iodine tincture cautery in combination with mechanical scraping of corneal epithelium (comprehensive method). Results Simple method of 10 eyes, 3 conjunctiva and cornea healing, the successful operation, 7 eyes were unsuccessful. In 10 eyes, 8 eyes had successful operation and 2 eyes did not succeed. There was a significant difference in the scores of 2 groups (P <0. 05). Conclusion The comprehensive method can more effectively damage the corneal epithelium and corneal stem cells, and improve the success rate of surgery.