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本文报告33例小儿肾病综合征肾穿刺活检结果。33例可归为难治性肾病综合征。结果示:临床诊为单纯性肾病及对激素治疗完全效应者并非都是微小病变型。本组病例以系膜增生性肾炎为最多见,且观察到该型免疫荧光强度低及单纯于系膜区沉积者时激素近期反应较好,而免疲荧光强度高且沉积于系膜区及血管壁者激素反应较差。HBsAg阳性血症以膜性肾病发生率最高,膜性增生性肾炎次之。
This article reports 33 cases of nephrotic syndrome in children with renal biopsy results. 33 cases can be classified as refractory nephrotic syndrome. The results showed that: Clinical diagnosis of simple nephropathy and hormone therapy are not all patients with minimal effect of micro-lesions. The group of patients with mesangial proliferative glomerulonephritis is the most common, and observed that the type of immunofluorescence intensity and mesangial deposition was simple when the recent good response hormone, and fatigue-free fluorescence intensity and deposited in the mesangial area and Vascular wall hormone response is poor. The incidence of membranous nephropathy is the highest in HBsAg-positive sepsis, followed by membranous proliferative glomerulonephritis.