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机体或细胞在低氧环境中可产生低氧诱导因子１（ＨＩＦ１）及多种类分子，通过转录水平参与对低氧反应性基因的调控，从而使机体或细胞进一步对低氧刺激作出复杂的病理生理性反应。其详细的生物学功能及具体的调节机制等问题还尚待研究
The body or cells in the hypoxic environment can produce hypoxia-inducible factor 1 (HIF 1) and many kinds of molecules, transcriptional level involved in the regulation of hypoxia-responsive genes, so that the body or cells to further hypoxia stimulation complex The pathophysiological response. Its detailed biological functions and specific regulatory mechanisms and other issues have yet to be studied