肿瘤生长依赖于肿瘤血管的形成 ,因此 ,如果能够有效地抑制或破坏肿瘤内部血管网络无疑为肿瘤治疗开辟一片新天地。一般来说 ,以肿瘤血管为靶子的治疗途径可归纳为 2条 :①干扰新生血管形成 ,包括直接抑制内皮细胞的能力 ,阻断内皮细胞降解周围基质的能力 ,阻断血管生成因子的 Tumor growth depends on the formation of tumor blood vessels, therefore, if it can effectively inhibit or destroy the internal vascular network of tumors undoubtedly open up a new world for cancer treatment. In general, the treatment of tumor blood vessels as the target can be summarized as two ways: ① interfere with neovascularization, including the ability to directly inhibit endothelial cells, endothelial cells to interrupt the degradation of the surrounding matrix capacity, blocking the angiogenic factor