论文部分内容阅读
目的探讨药物治疗对高血压患者颈动脉IMT及斑块形成的影响.方法将健康体检出252名原发性高血压患者根据其用药情况分成西药(A组),中药(B组)和中西药结合(C组),分别检测颈动脉内膜-中层厚度(IMT)和斑块情况,与未治疗组织进行对照.结果3组的IMT和斑块检出率明显低于对照组(P<0.05),C组则低于AB两组(P<0.001).结论控制高血压,特别是中西药物合用可延缓动脉硬化发展。
Objective To investigate the effects of medical therapy on the carotid IMT and plaque formation in hypertensive patients.Methods 252 patients with essential hypertension were divided into western medicine (group A), traditional Chinese medicine (group B) and western medicine (IMT) and plaque of carotid arteries were detected by immunohistochemistry (C group) and compared with untreated tissues.Results The IMT and plaque detection rate in the three groups were significantly lower than those in the control group (P <0.05 ), C group was lower than the AB two groups (P <0.001) .Conclusion Control of hypertension, especially the combination of Chinese and Western medicine can delay the development of atherosclerosis.