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目的探讨改良CHOPE治疗非霍奇金淋巴瘤的疗效。方法对12例非霍奇金淋巴瘤的患者采用改良CHOPE方案,连续应用2疗程以上判定疗效。结果 12例患者经2疗程以上治疗,完全缓解6例(50%),部分缓解4例(33.3%),明显进步3例(25%)。毒、副作用可耐受。结论本组治疗中,部分对其他化疗方案无效(如CHOP方案)的难治性和复发性非霍奇金淋巴瘤患者采用改良CHOPE方案仍有效,并可达完全缓解。该方案毒副作用可耐受,应用安全。
Objective To investigate the curative effect of modified CHOPE on non-Hodgkin’s lymphoma. Methods 12 cases of non-Hodgkin’s lymphoma patients with modified CHOPE program, continuous application of 2 courses or more to determine the efficacy. Results After 12 courses of treatment, 12 cases achieved complete remission in 6 cases (50%), partial remission in 4 cases (33.3%) and significant improvement in 3 cases (25%). Poisonous, side effects are tolerable. Conclusion In this group of treatment, some patients with refractory and recurrent non-Hodgkin’s lymphoma who are ineffective with other chemotherapy regimens (such as CHOP regimen) are still effective and can achieve complete remission with modified CHOPE regimen. The program side effects can be tolerated, application security.