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目的：分析和探讨细节护理对肿瘤术后化疗致抑郁情绪的干预价值。方法选取2013年5月~2015年6月于我院接受术后化疗治疗的患者68例，按照入院编号随机分成对照组和观察组两组，其中，对照组34例，对患者进行常规护理，观察组34例，在常规护理的基础上再对患者进行细节护理，应用ZUNG自评抑郁量表(SDS评分)和自动思维问卷(ATQ)对护理干预措施实施前后两组患者的抑郁和负性认知情况进行调查和对比分析。结果护理干预措施实施后，两组患者的抑郁和负性认知情况均有不同程度的改善，但观察组患者的SDS得分和负性认知得分分别为(34.76±6.41)分和(55.13±9.03)分，均明显低于对照组，对比有显著性差异(<0.05)。结论细节护理的实施，能够有效改善肿瘤术后化疗患者的抑郁情况，并降低患者的负性思维，具有一定的临床实用价值。“,”Objective To study the value of nursing intervention in patients with postoperative chemotherapy induced depression. Methods 34 patients were randomly divided into control group and observation group, two cases in control group, 34 cases in control group, two cases in observation group were treated with ZUNG self rating Depression Scale (SDS score) and automatic thought questionnaire (ATQ). Results After nursing intervention, two groups of patients with depression and negative cognitive situation have different degrees of improvement, but the observation group of patients with SDS score and negative cognitive score were (6.41±34.76) and (9.03 ±55.13), were significantly lower than the control group ( ﹤0.05).Conclusion The implementation of detailed nursing can effectively improve the depression of postoperative chemotherapy patients, and reduce the negative thinking, has a certain clinical practical value.