格雷失斯(Graves)病以甲状腺机能亢进(简称甲亢)、弥漫性甲状腺肿大和突眼为特征。少数Graves病病人眼部表现可在甲状腺功能正常甚至减退时出现;也可在甲亢症状出现之前发生;或只有突眼而无甲状腺疾病的表现,称为Graves眼病(GO)或眼型Graves病。几乎所有Graves病都伴有不同程度的突眼,但大多效属良性型,严重浸润性突跟(又称恶性突眼)仅占Graves病的3～5%,但治疗颇为棘手。 Graves disease is characterized by hyperthyroidism (hyperthyroidism), diffuse goiter and exophthalmos. Ocular manifestations in a minority of patients with Graves’ disease may occur when thyroid function is normal or even diminished; it may also occur before symptoms of hyperthyroidism occur; or only those with unaffected thyroid disease, known as Graves ophthalmopathy (GO) or Ocular Graves disease. Almost all Graves ’disease is associated with varying degrees of exophthalmos, but most of them are benign and severe infiltrative hits (also known as malignant exophthalmos) account for only 3 to 5% of Graves’ disease, but treatment is rather troublesome.