目前,全世界有数以百万计的人在从事金属、非金属及其他矿物的开采。矿物粉尘已成为极其重要的职业危害因素之一。吸入这些粉尘后对健康最重要的影响是肺的纤维化反应(尘肺)。众所周知,矿物粉尘在一定条件下可导致一系列严重的肺部疾患如矽肺、铍肺、煤工尘肺、硬金属肺纤维化以及石棉肺等。虽然流行病学调查和临床观察已积累了有关这类疾病的大量资料,但由于矿物粉尘引起的疾病往往在出现临床症状之前有一段很长的潜伏期,而流行病学方法又往往缺乏接尘个体的接触资 Millions of people around the world are currently engaged in the mining of metals, non-metals and other minerals. Mineral dust has become one of the most important occupational hazards. The most important health effect after inhaling these dusts is the pulmonary fibrosis (pneumoconiosis). It is well-known that under certain conditions, mineral dust can lead to a series of serious lung diseases such as silicosis, beryllium lung, coal worker’s pneumoconiosis, hard metal lung fibrosis and asbestosis. Although a plethora of data on these diseases have been accumulated in epidemiological and clinical observations, the disease caused by mineral dust often has a long incubation period before clinical signs appear, and epidemiological methods often lack individuals Contact information