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目的:探讨两种类型子宫内膜癌的发病年龄、手术-病理分期、组织学分级、肌层浸润及雌孕激素受体表达的差异,以期增强对非子宫内膜样癌的认识及重视。方法:对455例子宫内膜癌患者的临床病理资料进行回顾性分析。结果:两种类型子宫内膜癌的平均发病年龄、在绝经前后患者中的构成比、组织学分级、手术-病理分期、肌层浸润深度及雌、孕激素受体表达及淋巴结转移情况有统计学差异。结论:非子宫内膜样癌与子宫内膜样腺癌相比,患者发病年龄较大;在已绝经患者中所占比例远高于子宫内膜样腺癌;Ⅲ/Ⅳ期、中、低分化、雌孕激素受体阴性的比例明显高于内膜样腺癌,更易发生深肌层浸润和淋巴结转移。
OBJECTIVE: To investigate the age, pathological stage, histological grade, myometrial invasion and the difference of estrogen, progesterone receptor expression between two types of endometrial carcinoma so as to enhance their understanding and emphasis on non-endometrial carcinoma. Methods: The clinical and pathological data of 455 cases of endometrial carcinoma were retrospectively analyzed. Results: The average age at onset of the two types of endometrial cancer in patients before and after menopause, histological grade, surgical - pathological staging, depth of myometrial invasion and estrogen and progesterone receptor expression and lymph node metastasis statistics Differences Conclusion: Compared with endometrioid adenocarcinoma, non-endometrioid adenocarcinoma has a relatively older age of onset and a much higher proportion of patients with postmenopausal endometrial adenocarcinoma. Stage III / IV, middle and low Differentiation, estrogen and progesterone receptor negative ratio was significantly higher than endometrioid adenocarcinoma, more prone to deep myometrial invasion and lymph node metastasis.