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本报告是关于加拿大纽芬兰荧石矿矿工肺癌与氡子体暴露关系队列研究 １９８８ 年报告的续篇，观察时间在前一报告（１９５０～１９８４ 年）的基础上增加了 ６年（１９８５～１９９０ 年）。调查了地下荧石矿矿工 １ ７４３名，地面工人３２１ 名。地下矿工平均暴露 ５．７ 年的平均氡子体累积暴露量为 ３８２．８ Ｗ Ｌ Ｍ （工作水平月）。结果：１９５０～１９９０ 年间，对地下矿工共累积观察４８ １８９ 人年，在此期间，１ ７４３ 名矿工中有 ５７６ 名死亡，死亡者中 ２２８ 名死于癌症，其中 １３８ 名为肺癌，而同期地面工人仅有８ 例死于肺癌。经对到达年龄和年代的调整，肺癌死亡相对危险（ Ｒ Ｒ）与氡子体累积暴露量关系的分析结果表明， Ｒ Ｒ 随累积暴露量的增加而增加。使用连续的 Ｗ Ｌ Ｍ 估算的肺癌超额相对危险（ Ｅ Ｒ Ｒ）系数（ Ｅ Ｒ Ｒ／ Ｗ Ｌ Ｍ）为０．００７０（９５％ Ｃ Ｉ：０．００４４～０．０１１４），绝对超额危险系数（例数 １０６ 人年１ Ｗ Ｌ Ｍ １）为６．４（９５％ Ｃ Ｉ：５０～８．０）。肺癌 Ｅ Ｒ Ｒ 系数随到达年龄的增加而减少，＜ ５０ 岁是 ０．０２５３，而≥７０ 岁为 ０．００２１，但 Ｅ Ｒ Ｒ 系数不受第一次受照年龄的影响?
This report is a continuation of the 1988 report of the cohort study on the relationship between lung cancer and neon seeds exposed by the fluorite miners in Newfoundland, Canada. The observation time was increased by 6 years (1985-1990) based on the previous report (1950-1984). ). 1 743 underground fluorite miners and 321 ground workers were investigated. The average cumulative radon cumulative exposure of underground miners for 5.7 years was 382.8 WLM (working month). Results: During the period from 1950 to 1990, a total of 48 189 person-years were observed for underground miners. During this period, 576 of the 1,743 miners died. Of the 227 deaths, 228 died of cancer, 138 of them were lung cancer, and the same period Only 8 cases of workers died of lung cancer. The analysis of the relationship between the relative risk of death from lung cancer (R R) and cumulative cumulative sputum exposure after adjusting for age and age of arrival showed that R R increased with cumulative exposure. The excess relative risk (E R R) coefficient (ERR R/W L M) for lung cancer estimated using the continuous WL M was 0.0070 (95% C I: 0.0044 to 0.0114), and the absolute excess risk factor (The number of cases of 10-6 years-1 LM M-1) is 6.4 (95% C I: 50-8.0). The E R R coefficient of lung cancer decreases with the age of arrival, < 0.0253 for 50 years and 0.0021 for ≥ 70 years, but the E R R coefficient is not affected by the age of first exposure.