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[目的]对复发性脑梗死患者首次发病后使用阿司匹林情况的调查,探讨引起其临床应用不规范的一些主要原因。[方法]从2003年9月～2008年3月住院的479例脑梗死患者中筛选出复发性脑梗死118例,调查其首次发病后使用阿司匹林的情况,分析阿司匹林使用不规范的原因。[结果]118例复发性脑梗死患者首次发病后在住院期间均接受阿司匹林75～150mg/d治疗。92例(77.97%)患者出院后阿司匹林使用不规范;其中,63例(53.39%)患者虽坚持服用阿司匹林,但37例患者剂量过低,占58.73%(37/63);55例(46.61%)患者间断服用阿司匹林。阿司匹林使用不规范的主要原因为:患者担心不良反应;患者嫌麻烦;患者或家属认为无效;医生未告知需长期服药;患者未坚持神经内科门诊随访,未接受专科医生指导;门诊医生随访中忽略询问使用情况;患者因出现副作用(胃肠道不适、皮疹)而停药。[结论]相当比例的复发性脑梗死患者首次发病后使用阿司匹林剂量过低及未能坚持长期服用。应对脑梗死患者加强卒中健康教育,以提高阿司匹林使用依从性。
[Objective] To investigate the use of aspirin in patients with recurrent cerebral infarction after the first episode to explore some of the main causes of non-standard clinical application. [Method] A total of 118 patients with recurrent cerebral infarction were screened out from 479 patients with cerebral infarction who were hospitalized from September 2003 to March 2008. The aspirin was investigated after the first onset and the reasons for the non - standard use of aspirin were analyzed. [Results] The 118 patients with recurrent cerebral infarction received aspirin 75-150 mg / d during the first hospitalization after hospital admission. Among them, 63 (53.39%) patients insisted on taking aspirin, but 37 patients (58.73%, 37/63) had low dose; 55 patients (46.61% Patients discontinued aspirin. The main reasons for the non-standard use of aspirin are as follows: patients are worried about adverse reactions; patients are troublesome; patients or their families think invalid; the doctors do not tell them to take long-term medication; patients do not insist on neurology outpatient follow-up and are not under the guidance of specialists; Inquire about usage; patients discontinued due to side effects (gastrointestinal upset, rash). [Conclusion] A significant proportion of patients with recurrent cerebral infarction use aspirin for the first time after the low dose and failed to adhere to long-term use. Stroke health education should be strengthened in patients with cerebral infarction to improve aspirin use compliance.