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目的:分析酮症倾向2型糖尿病合并非酒精性脂肪肝的临床特征和相关因素。方法:选2型糖尿病患者合并非酒精性脂肪肝患者390例,分为酮症倾向糖尿病和非酮症糖尿病患者两组,比较两组年龄、性别、BMI、空腹血糖、糖化血红蛋白、血脂、空腹C肽、高血压史、吸烟史、家族史、CRP的差异,并进行Logistic回归分析。结果:1酮症倾向糖尿病组中男性比例、BMI、高甘油三酯、高胆固醇、空腹C肽明显高于非酮症糖尿病患者组(P<0.05);2Logistic回归显示男性、BMI、高甘油三酯、空腹C肽是酮症倾向2型糖尿病合并非酒精性脂肪肝的主要危险因素(P<0.05)。结论:男性、BMI、高甘油三酯、空腹C肽是酮症倾向2型糖尿病合并非酒精性脂肪肝的主要危险因素。
Objective: To analyze the clinical characteristics and related factors of ketosis-prone type 2 diabetes mellitus patients with non-alcoholic fatty liver disease. Methods: A total of 390 patients with type 2 diabetes mellitus complicated with non-alcoholic fatty liver disease were divided into two groups: age, sex, BMI, fasting blood glucose, glycosylated hemoglobin, lipids, fasting serum C peptide, history of hypertension, smoking history, family history, CRP, and Logistic regression analysis. Results: 1 The male ratio, BMI, high triglyceride, high cholesterol and fasting C-peptide in ketosis prone diabetic group were significantly higher than those in nonketotic diabetic patients (P <0.05); 2Logistic regression showed that male, BMI, Estrogen and fasting C-peptide were the major risk factors for ketosis-prone type 2 diabetes with non-alcoholic fatty liver (P <0.05). Conclusion: Male, BMI, high triglyceride and fasting C-peptide are the main risk factors of ketosis-prone type 2 diabetes with non-alcoholic fatty liver disease.