我们对常见的几种呼吸系疾病的血清、胸水和支气管肺泡灌洗液(BALF)中血管紧张素转换酶(ACE)活性进行了测定,以了解ACE变化及其临床意义。与对照组比较,慢性肺心病、肺炎、肺癌的血清ACE活性降低,结节病血清ACE活性明显升高;胸水ACE活性测定有助于良、恶性胸水的鉴别诊断;BALF中ACE活性测定对弥漫性间质性肺疾病活动性的判断有一定价值。 We measured the activity of ACE in serum, pleural effusion and bronchoalveolar lavage fluid (BALF) of several common respiratory diseases in order to understand the changes of ACE and its clinical significance. Compared with the control group, the serum ACE activity in chronic pulmonary heart disease, pneumonia and lung cancer was decreased, and the serum ACE activity in sarcoidosis was significantly increased. The determination of ACE activity in pleural effusion was helpful for differential diagnosis of pleural effusion and malignant pleural effusion. Sexual interstitial lung disease activity has some value judgments.