论文部分内容阅读
目的 :对瑞格列奈联合二甲双胍治疗糖尿病的临床效果进行观察。方法 :选取2013年4月~2015年4月我院收治的糖尿病患者116例作为观察对象,按照抽签法随机分为观察组(n=58)和对照组(n=58),观察组患者采用瑞格列奈联合二甲双胍来进行治疗,对照组患者则采用格列本脲联合二甲双胍来进行治疗。观察两组患者的空腹血糖(FPG)、餐后血糖(PBG)、糖化血红蛋白(Hb A1c)等指标的变化情况,并对两组患者的治疗情况进行对比。结果 :在治疗后,观察组患者的各项指标改善情况均要优于对照组,组间差异具有统计学意义(P<0.05);观察组患者的治疗总有效率为93.1%,明显高于对照组的77.6%,组间差异明显,具有统计学意义(X2=5.5829;P<0.05)。结论 :采用瑞格列奈联合二甲双胍治疗糖尿病具有较好的治疗效果,患者的各项指标恢复情况较好,有效缓解了患者的病痛困扰,具有较高的临床价值,值得推广。
Objective: To observe the clinical effect of repaglinide combined with metformin in the treatment of diabetes mellitus. Methods: A total of 116 diabetic patients treated in our hospital from April 2013 to April 2015 were selected as observation subjects and randomly divided into observation group (n = 58) and control group (n = 58) according to random sampling method. Patients in observation group Repaglinide combined with metformin for treatment, while patients in the control group were treated with glyburide combined with metformin. The changes of fasting blood glucose (FPG), postprandial blood glucose (PBG) and HbA1c in two groups were observed and compared between the two groups. Results: After treatment, the improvement of each index in the observation group was better than that in the control group, the difference was statistically significant (P <0.05); the total effective rate in the observation group was 93.1%, which was significantly higher than that of the control group The control group, 77.6%, significant difference between groups, with statistical significance (X2 = 5.5829; P <0.05). Conclusion: The treatment of diabetes with repaglinide and metformin has a good therapeutic effect, the recovery of all indicators of patients is better, effectively relieving the patient’s pain and distress, with high clinical value, it is worth promoting.