自Edwards等(1960)首次报告一例18三体综合征伴发多发性先天性畸形以来,国外已有不少文献描述。1983年6月我们在尸检工作中遇到一例18三体胎儿的多发性先天性畸肜,报告如下。病例报告 临床资料: 胎儿,男性,2胎0产。其母亲26岁,因停经6个月,不觉胎动而做“B超”检查,诊断为无脑畸 Since Edwards et al. (1960) first reported a case of trisomy 18 with multiple congenital malformations, there are many foreign literature described. In 1983 June we met an autopsy in 18 cases of trisomy 18 multiple congenital malformations, the report is as follows. Case report clinical data: fetus, males, 2 fetuses 0 production. The 26-year-old mother, due to menopause for 6 months, fetal movement and do “B-ultrasound” examination, diagnosis of no brain abnormalities