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目的分析１４例１６个周期赠卵体外受精．胚胎移植（ＩＶＦ－ＥＴ）治疗的临床结果。方法采用长周期ＧｎＲＨａ／Ｇｎ超促排卵方案、受卵者采用激素替代治疗（ＨＲＩ）或ＧｎＲＨａ／ＨＲＴ方案，应用戊酸雌二醇（ＥＶ）１２－４２ｄ，供卵者经阴道取卵与受者丈夫的精子行体外受精及胚胎培养４８－７２ｈ于受卵者应用黄体酮３－５ ｄ后行胚胎移植。妊娠后继续用雌、孕激素治疗直至妊娠１２周为止。结果每周期取卵数（１４.１±５.２）个（ ７－２２个），每周期移植胚胎数（４.３±１.６个），１５个移植周期中。临床妊娠８次（５３.３％） ，胚胎着床率３００％（８／５８）．３例于早期流产，５例继续妊娠达８－３５周。讨论赠卵ＩＶＦ－ＥＴ是治疗卵巢功能衰退患者的有效方法。应用雌激素时间的长短变异范围较大，不影响妊娠，用孕激素３－５ｄ后行移植胚胎取得了良好的妊娠率。
Objective To analyze 14 cases of 16 cycles of egg donation in vitro fertilization. Clinical outcome of embryo transfer (IVF-ET) treatment. Methods Long-term GnRHa / Gn hyperstimulation was used. Egg recipients were treated with hormone replacement therapy (HRI) or GnRHa / HRT regimen. Estradiol valerate (EV) 12-42d, Her husband’s sperm IVF and embryo culture 48-72h in the recipient of ovarian progesterone 3-5d after embryo transfer. Pregnancy continue to use estrogen and progesterone until the 12th week of pregnancy. Results The numbers of oocytes retrieved each week (14.1 ± 5.2) (7-22), the number of embryos transferred per week (4.3 ± 1.6) and 15 cycles. Clinical pregnancy 8 times (53.3%), embryo implantation rate of 300% (8/58). 3 cases of early abortion, 5 cases of pregnancy continued for 8-35 weeks. Discussing donated eggs IVF-ET is an effective treatment for patients with ovarian failure. Application of estrogen time variation of the scope of the larger, does not affect the pregnancy, with progesterone transplant embryos after 3-5d achieved a good pregnancy rate.