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用三环类药物对成年人抑郁症发作应进行优化治疗,可通过选择药物,调整剂量和治疗时间及测定血浆药物浓度而实现。 1.药物选择 治疗剂量不足可能是某种药物无效的常见原因,不应轻易放弃该药。医生不能单凭动物的最初反应,家属态度或医生个人意愿选用药物,精神药理学家根据药物血浆浓度与治疗效果的关系选用药物。他们所欣赏的三环类药物有丙咪嗪、去甲替林、脱甲丙咪嗪。
Tricyclic drugs for depression in adults should be optimized treatment of seizures, by selecting drugs, adjusting the dose and treatment time and determination of plasma drug concentration achieved. 1. Drug selection and treatment of insufficient doses may be a common cause of ineffective drugs, should not easily give up the drug. Physicians can not choose the drugs solely based on the initial reaction of the animals, their relatives’ attitude, or their personal wishes. The psychopharmacologists choose the drugs according to the relationship between the drug plasma concentration and the therapeutic effect. The tricyclics they admired were imipramine, nortriptyline, desipramine.