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抗胆碱药是急性有机磷农药中毒(AOPP)的重要解毒剂,传统应用的抗胆碱药阿托品毒副作用较大,患者对其耐受性个体差异也较大,其临床治疗剂量与中毒剂量接近,易发生阿托品中毒甚至死亡[1]。2006年2月至2008年4月我科共收治口服有机磷中毒患者38例,全部使用长托宁与解磷定救治。我
Anticholinergic drugs are an important antidote to acute organophosphorus pesticide poisoning (AOPP). The traditional application of anticholinergic atropine has a large side effect, and patients are also more tolerant of individual differences. The clinical treatment dose is similar to the poisoning dose, and is prone to atropine poisoning Even death [1]. February 2006 to April 2008, our department received a total of 38 patients with oral organophosphate poisoning, all using penehyclidine and phosphate solution for treatment. I