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目的:研究不同剂量X射线全身照射对小鼠淋巴结皮质细胞凋亡的影响。方法:采用原位末端标记(TUNEL)法检测高、低剂量电离辐射后肠系膜淋巴结皮质中细胞凋亡情况。结果:淋巴结皮质的不同区域对高、低剂量电离辐射的敏感性均不同。结论:低剂量辐射所致的小结间区及深皮质区凋亡细胞数减少,是低水平辐射兴奋效应的一种表现。
Objective: To study the effects of different doses of X-rays on apoptosis of mouse lymph node cortical cells. Methods: The apoptosis of mesenteric lymph node cortex in high and low dose ionizing radiation was detected by TUNEL method. Results: The sensitivity of different regions of lymph node cortex to high and low doses of ionizing radiation were different. Conclusion: The decrease of apoptotic cells in the interlobular and cortical areas caused by low-dose radiation is a manifestation of the low-level radiation excitement effect.