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作者在1972～1984年间用统一剂量~(131)I740MBq(20mCi)治疗有甲亢表现的单个毒性自主功能性甲状腺结节病人52例,平均年龄51.2±11.2岁,女:男为3.3∶1,平均血清T_3为4.3±1.1nmol/L(正常值1.8～2.9);T_4为186±44nmol/L(正常值65～140);24小时摄碘率为52±12%.放射性碘和锝显像显示单个热结节伴结节外组织摄碘功能受抑制.其中12例在服~(131)I前曾用抗甲状腺药物治疗.结果:在~(131)I治疗后6个月时,全部52例都转为甲状腺功能正常,不需服用抗甲状腺药物.有一
The authors treated 52 patients with single-toxic autonomic functional thyroid nodules with a single dose of 131 IMBM (20 mCi) from 1972 to 1984 with an average age of 51.2 ± 11.2 years and a mean male-female ratio of 3.3: 1 Serum T_3 was 4.3 ± 1.1 nmol / L (normal value 1.8 to 2.9); T_4 was 186 ± 44 nmol / L (normal value was 65 to 140); iodine uptake rate was 52 ± 12% at 24 hours. Radioiodine and technetium scintigraphy A single nodule with nodular extranodal tissue was found to inhibit iodine uptake, of which 12 were treated with antithyroid drugs before taking 131I. RESULTS: Six months after 131I treatment, all 52 Cases are converted to normal thyroid function, do not take anti-thyroid drugs