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目的研究分析高铅血症儿童肠道菌群构成变化情况。方法 30例高铅血症儿童为观察组,30例健康儿童为对照组,均检测两组儿童肠道菌群中乳酸杆菌、双歧杆菌、肠球菌和大肠杆菌的数量以及肠道内双歧杆菌和大肠杆菌数量对数值的比值(B/E值)。结果两组儿童肠道菌群数量比较结果显示,观察组儿童的双歧杆菌、乳酸杆菌、大肠杆菌明显低于对照组儿童,差异有统计学意义(P<0.05)。观察组儿童B/E值为(0.784±0.334),对照组儿童B/E值为(1.213±0.351),两组B/E值比较差异有统计学意义(P<0.05)。结论高铅血症儿童的体内有肠道菌群紊乱的情况发生。
Objective To study the changes of gut flora in children with hyperlipidemia. Methods Thirty children with hypercholesterolemia were selected as observation group and 30 healthy children as control group. The numbers of lactobacilli, bifidobacteria, enterococci and Escherichia coli in intestinal flora of two groups were detected, And the number of E. coli ratio (B / E value). Results The results of comparison of intestinal microflora of children in the two groups showed that the Bifidobacterium, Lactobacillus and Escherichia coli in the observation group were significantly lower than those in the control group (P <0.05). The B / E value of the observation group was (0.784 ± 0.334) and that of the control group was (1.213 ± 0.351). There was significant difference between the two groups (P <0.05). Conclusion In children with hyperlipidemia, intestinal flora disorder occurs.