近年来迅速取得进展的第3代先锋霉素剂对β-内酰胺酶显示出较强的抵抗性,不仅扩大了抗菌谱,而且对革兰氏阴性杆菌的抗菌力也显著增强。然而此类药剂的抗菌力越强其临床使用越应慎重,以避免使用本剂可能出现的菌群失调及伴随强力杀菌作用的同时出现药物副作用。尤其应尽量控制本剂用于术后感染 In recent years, the third generation of Vanguard ADM that made rapid progress has shown strong resistance to β-lactamase, which not only expands the antibacterial spectrum but also significantly enhances the antibacterial activity of Gram-negative bacilli. However, the stronger the antibacterial activity of such agents, the more careful the clinical use, to avoid the possible use of this agent may appear flora and strong sterilization accompanied by drug side effects. In particular, should try to control the agent for postoperative infection