内毒素休克是临床常见的急危重症 ,尽管半个世纪以来对其研究有了很大进展 ,但其病死率仍居高不下。因此 ,内毒素休克仍是医学科学研究的重要课题。肿瘤坏死因子 (tumornecrosisfactor,TNF)是脂多糖 (lipopolysaccharide ,LPS)作用于单核巨噬细胞所释放的一种多肽类物质。分为T Endotoxic shock is a clinically common and critically ill condition and despite its considerable advances in research for half a century, its mortality remains high. Therefore, endotoxic shock is still an important issue in medical science. Tumor necrosis factor (TNF) is a polypeptide released by lipopolysaccharide (LPS) on monocytes and macrophages. Divided into T