白念珠菌在宿主体内定居并致病归因于它所具有的某些毒性,包括粘附,二态性,转化现象,影响宿主免疫系统,与其他细菌协同作用,产生细胞外酶如蛋白酶,磷脂酶等。某些抗真菌药物的作用即是通过抑制粘附,影响酶产生等而实现的。本文目的是评价制霉菌素和氟康唑对糖尿病患者白念珠菌毒力的影响。 材料和方法 108例糖尿病患者,其中88例有 Candida albicans settles in the host body and is attributed to some of its toxicity, including adhesion, dysentery, transformation, affecting the host immune system, synergizing with other bacteria, producing extracellular enzymes such as proteases, Phospholipase and so on. Some antifungal drugs that is through the inhibition of adhesion, affect the production of enzymes and so on. The purpose of this article is to evaluate the effects of nystatin and fluconazole on C. albicans virulence in diabetic patients. Materials and Methods 108 cases of diabetic patients, of which 88 cases have