Studying the effect of geometrically irregular bodies on the mechanical behavior of fault activity is of significance in understanding the seismic activity along a fault zone. By using rock mechanics ex- periment with medium-scale samples, we have studied the effect of fault jogs, the most common irregularity along fault zones, on frictional behavior. The research indicates that extensional fault jog can be easily fractured because of its low strength and the fractured jog has no obvious resistance to fault sliding, and the micro-fractures occurring in the jog are indicative of stick-slip along the faults. The fault zone containing extensional jogs is characterized by velocity weakening and can be described by rate and state friction law. Compressional fault jog makes fault sliding more difficult because of its high fracturing strength, but the micro-fractures occurring in the tensile areas around fault ends at higher stress level can provide necessary condition for occurrence of stick-slip along the faults before the jog is fractured and thus act as precursors of fault instability. Compression jog can be taken as a stable indicator of fault segmentation until the jog is completely fractured and two faults are linked. Studying the effect of geometrically irregular bodies on the mechanical behavior of fault activity is of significance in understanding the seismic activity along a fault zone. By using rock mechanics ex- periment with medium-scale samples, we have studied the effect of fault jogs, the most common irregularity along fault zones, on frictional behavior. The research indicates that extensional fault jog can be easily fractured because of its low strength and the fractured jog has no obvious resistance to fault sliding, and the micro-fractures occurring in the jogog of stick-slip along the faults. The fault zone containing extensional jogs is characterized by velocity weakening and can be described by rate and state friction law. Compressional fault jog makes fault sliding more difficult because of its high fracturing strength, but the micro-fractures occurring in the tensile areas around fault ends at higher stress level can provide necessary condition for occurrence of stick -slip along the faults before the jog is fractured and thus act as precursors of fault instability. Compression jog can be taken as a stable indicator of fault segmentation until the jog is completely fractured and two faults are linked.