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目的探讨老年肺癌患者医院感染的临床特点。方法对我院5年间62例老肺癌患者医院感染发生率、感染部位、致病菌和易感因素等进行回顾性分析,并与同期非老年组进行比较。结果老年组发生医院感染率为72.5%,高于同期非老年组的33.9%,P<0.01。感染部位以呼吸系统和口腔多见,多部位感染、重症感染高于非老年组,致病菌革兰氏阴性杆菌为骨髓抑制,粒细胞缺乏者感染率明显增高。结论老年肺癌患者医院感染发生率高,骨髓抑制、粒细胞缺乏为主要易感因素。治疗应及时应用有效抗生素,加强综合支持治疗。
Objective To investigate the clinical features of nosocomial infection in elderly patients with lung cancer. Methods The incidence of nosocomial infection, the site of infection, pathogens and susceptibility factors in 62 elderly patients with primary lung cancer in our hospital over a five-year period were retrospectively analyzed and compared with those of non-elderly patients in the same period. Results The incidence of nosocomial infection in the elderly group was 72.5%, which was higher than 33.9% of the non-elderly group in the same period (P <0.01). Infected parts of the respiratory system and the oral cavity more common, multi-site infection, severe infection was higher than non-elderly group, pathogenic bacteria Gram-negative bacilli were myelosuppressive, agranulocytosis infection was significantly higher. Conclusion The incidence of nosocomial lung cancer in elderly patients with high incidence of bone marrow suppression, neutropenia as the main susceptibility factors. Treatment should be timely and effective antibiotics to enhance comprehensive supportive care.