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用剌五加全株制成注射液,供静脉点滴用,室温保存8年澄明度未见变化。药理实验表明,对脑垂体后叶素引起的家兔急性心肌缺血有保护作用,可明显增加家免和猫离体心脏冠脉流量,对结扎犬冠脉前降支和第三分支引起的心肌梗塞区有缩小作用。临床用于治疗冠心病83例和急性闭塞性脑血管病67例,以低分子右旋糖酐注射液为对照组,前者疗效与对照组相似。后者高于对照组(P<0.01),且副作用小。
With the assassination of the whole plant made of injection, for intravenous drip, clear at room temperature for 8 years no change. Pharmacological experiments show that pituitrin-induced acute myocardial ischemia in rabbits have a protective effect, can significantly increase home-free and cat heart coronary flow, the canine ligation of the coronary artery and the third branch of the coronary artery caused Myocardial infarction area has reduced role. Clinical treatment of coronary heart disease in 83 cases and 67 cases of acute occlusive cerebrovascular disease, low molecular weight dextran injection as the control group, the former effect similar to the control group. The latter was higher than the control group (P <0.01), and the side effects were small.