论文部分内容阅读
据科学网2016年4月28日报道,北京大学生物动态光学成像中心谢晓亮、白凡实验组在细菌耐药性的分子机制研究领域取得了3个重要进展:1使用单分子活体荧光成像技术,发现持留菌中积累的抗生素较少,原因是持留菌增强的外排活动,表明高效地将抗生素泵出细胞也是持留菌形成的一个重要机制;2通过转录组基因测序,进一步证实了多重
According to a report from ScienceNet on April 28, 2016, Xie Xiaoliang and Bai Fan experimental group of Biodynamic Dynamic Optical Imaging Center of Peking University have made three important advances in the study of the molecular mechanism of bacterial resistance: 1 Using single-molecule in vivo fluorescence imaging technology, It was found that less antibiotics were accumulated in the residing bacteria due to the increased efflux activity of the retained bacteria, indicating that the efficient pumping of antibiotics out of the cells is also an important mechanism for the formation of retentive bacteria; 2 further confirmation of multiplexes by transcriptome gene sequencing.