论文部分内容阅读
目的:探析丁丙诺啡透皮贴剂与芬太尼透皮贴剂在治疗慢性非癌性疼痛中的疗效。方法:选取我院60例慢性非癌性疼痛患者,对其临床资料进行回顾性分析,根据数字随机方式将其分为研究组和对照组,各为30例,研究组采取丁丙诺啡透皮贴剂治疗,对照组采取芬太尼透明皮贴剂治疗,比较两组治疗前后的VAS及不良反应。结果 :治疗后,研究组VAS改善率为70.00%,对照组为57.14%,两组比较差异显著,P<0.05;研究组患者皮肤瘙痒发生率3.3%明显低于对照组16.7%,比较差异P<0.05。结论:应用丁丙诺啡透皮贴剂治疗慢性非癌性疼痛中的疗效较好,显著改善VAS评分,安全性较好,值得推广。
Objective: To investigate the efficacy of buprenorphine transdermal patch and fentanyl transdermal patch in the treatment of chronic non-cancerous pain. Methods: A total of 60 patients with chronic non-cancerous pain in our hospital were enrolled and their clinical data were retrospectively analyzed. According to the random numbers, they were divided into study group and control group, with 30 cases in each group. The study group adopted buprenorphine Skin patch treatment, the control group took fentanyl transparent skin patch treatment, VAS and adverse reactions were compared between the two groups before and after treatment. Results: After treatment, the improvement rate of VAS was 70.00% in the study group and 57.14% in the control group, with significant difference between the two groups (P <0.05). The incidence of pruritus in the study group was significantly lower than that in the control group (3.3% vs 16.7%, P> <0.05. Conclusion: The application of buprenorphine transdermal patch in the treatment of chronic non-cancerous pain has good curative effect, significantly improves the VAS score, and is safe and worthy of promotion.