本文作者研究了小自鼠实验性肝损伤和铁代谢紊乱对系统性真菌感染的影响。方法:将4周龄的健康雄性小鼠分成3组。第1组为肝损伤后真菌接种组(16只),以D(+)半乳糖胨(100mg/0.2ml)腹腔注射诱导肝损伤,在注射48小时肝损伤高峰期尾静脉注射白念珠菌悬液(2×10~7/0.2ml);第2组为无肝损伤真菌接种组(19只),注射菌量与1组相同;第3组为对照组(10只),各组观察21天后 The authors studied the effects of experimental autoimmune liver injury and iron metabolism disorders on systemic fungal infections in mice. Methods: Healthy 4-week-old male mice were divided into 3 groups. Group 1 was inoculated intraperitoneally with heparin (100mg / 0.2ml) into liver injury induced by fungal inoculation group after hepatic injury (16), and Candida albicans suspension was injected through caudal vein at the peak of liver injury (2 × 10 ~ 7 / 0.2ml). The second group was inoculated with fungus without liver injury (19 mice), and the number of inoculated bacteria was the same as that of the first group. The third group was the control group (10) Days later