论文部分内容阅读
采用ＡＰＡＡＰ法和ＥＬＩＳＡ法对３５例肺炎支原体肺炎（ＭＰＰ）患儿急性期和恢复期外周血Ｔ淋巴细胞亚群（ＣＤ３、ＣＤ４、ＣＤ８）及血清可溶性白细胞介素－２受体（ｓＩＬ－２Ｒ）进行测定。ＭＰＰ患儿急性期和恢复期ＣＤ４、ＣＤ４／ＣＤ８比值均明显低于对照组（Ｐ均＜０．０１）；ＣＤ８明显高于对照组（Ｐ均＜０．０５）；ＣＤ３与对照组无显著性差异。在ＭＰＰ的急性期和恢复期，ｓＩＬ－２Ｒ水平明显高于对照组（Ｐ均＜０．０１）。急性期ＣＤ８、ＣＤ４与ｓＩＬ－２Ｒ水平呈高度正、负相关。提示Ｔ淋巴细胞功能的紊乱及ｓＩＬ－２Ｒ水平的改变与ＭＰＰ的发生密切相关。
The levels of peripheral blood T lymphocyte subsets (CD3, CD4, CD8) and serum soluble interleukin-2 receptor (sIL-2R) in 35 children with Mycoplasma pneumoniae pneumonia (MPP) in acute and convalescent phase were detected by APAAP and ELISA ). The ratios of CD4 and CD4 / CD8 in acute and convalescent MPP children were significantly lower than those in control group (all P <0.01); CD8 was significantly higher than that in control group (all P <0.05); there was no significant difference between CD3 and control group Sex differences. The levels of sIL-2R in acute and convalescent MPP were significantly higher than those in control group (all P <0.01). Acute phase CD8, CD4 and sIL-2R levels were highly positive and negative correlation. Tip T lymphocyte dysfunction and sIL-2R level changes and the occurrence of MPP are closely related.