[七里元亮,他:制御,1986;30(8):475(日文)]本文首先对血糖调节机构作了控制理论分析,建立了血糖调节过程动态的数学模型。用比例加微分和一阶惯性环节表示胰岛素分泌的动态特性,即其传递函数为 k_p/(1+T_1S)+K_dS/(1+T_2S)。并写出了胰岛素对血糖作用的动态方程,指出胰高糖素的分泌特性。接着分析了糖尿病患者上述动态特性的变化。在胰岛素分泌方面,早期以微分项成分降低较显著;随病情的进展,比例成分的增益也下降,而胰岛素对血糖的作用也降低。根据上述分析,为弥补糖尿病人这些调节机构的缺陷,发展了 [Qili yuan bright, he: system Yu, 1986; 30 (8): 475 (Japanese)] In this paper, the blood glucose regulation mechanism made a theoretical analysis of the control, the establishment of a dynamic mathematical model of blood glucose regulation process. The dynamic characteristics of insulin secretion are expressed as ratio plus differential and first-order inertia, that is, the transfer function is kp / (1 + T_1S) + KdS / (1 + T_2S). And wrote a dynamic equation of insulin on blood glucose, glucagon secretion characteristics. Then analyze the changes in the above dynamic characteristics of diabetic patients. In terms of insulin secretion, the early differential component decreased more significantly; with the progress of the disease, the proportional component of the gain also declined, while the role of insulin on blood glucose is also reduced. Based on the above analysis, in order to make up for the defects of these regulatory institutions of diabetic patients, developed