治疗心绞痛,过去主要是以硝酸甘油舌下给药使其缓解,常以口服硝酸异山梨醇等硝酸盐来预防。但是,由于药效持续时间短,必须频繁给药,最近上市的长效硝酸盐制剂,每日只需给药2—3次即可,此药特别适用于预防夜间及黎明的心绞痛发作,下面,就最近开发的划时代的经皮给药疗法(每日给药一次)作一概述。药物的长效透皮系统,最初是1980年在美国为预防晕动症而出售的东莨菪碱透皮 Treatment of angina in the past mainly to nitroglycerin sublingual administration to ease, often with oral nitration of isosorbide nitrates to prevent. However, due to the short duration of the drug, it must be frequently administered. Recently listed long-acting nitrates can be administered only 2-3 times a day. This medicine is especially suitable for preventing angina attacks at night and dawn. , An overview of the recently developed epoch-making transdermal drug delivery (once daily). The drug’s long-acting transdermal system was originally sold as scopolamine transdermal in the United States in 1980 for the prevention of motion sickness