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应用间接EUSA法测定96例小儿病毒性心肌炎柯萨奇病毒E特异性IgM(CVB。-IM牡)。结果阳性30例,总阳性率31.3%:19例健康儿中有1例阳性,阳性率5.3%,两者比较差异有显著意义(x=4,20,P<0.05)病程<2月者阳性率为42.4%(28/66例).病程2~6月者阳性率为7.7(1/13例),病程>6月者阳性率为5.9%(1/17例).后两组与病程<2月组比较差异均显著(分别为4,9.6.61,P均<(0.05)。提示CVB-IM测定对小儿病毒性心肌炎病原学的早期诊断有临床意义
Indirect EUSA method was used to detect Coxsackievirus E-specific IgM (CVB.-IM) in 96 pediatric patients with viral myocarditis. The positive rate was 31.3%. The positive rate was 5.3% in 19 healthy children. The difference was significant (x = 4,20, P <0.05) Duration of <2 months positive rate was 42.4% (28/66 cases). The positive rate was 7.7% (1/13 cases) in 2 ~ 6 months and 5.9% (1/17 cases) in duration> 6 months. The difference between the latter two groups and the course of <2 months was significant (4,9.6.61 respectively, P <0.05), which indicated that the CVB-IM was clinically useful in the early diagnosis of pediatric viral myocarditis etiology significance