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疫苗的热稳定性与冻干保护剂的配方密切相关。目前使用的乙脑活疫苗冻于保护剂保护效果不十分理想,疫苗稳定性较差。因此,我们对现行保护剂配方进行了一些调整,希望能找到更好的配方,进一步提高疫苗质量。配方Ⅰ:现行生产用配方;配方Ⅱ:在配方1的基础上,补加人血白蛋白
The thermal stability of the vaccine is closely related to the formulation of the lyoprotectant. Currently used JE live vaccine in protective effect of protective agent is not very satisfactory, the vaccine is less stable. Therefore, we have made some adjustments to the current formulation of protective agents in the hope of finding better formulations and further improving the quality of vaccines. Formulation I: The current production formula; Formulation II: On the basis of formula 1, additional human serum albumin