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目的分析尿道下裂患者术后抑郁症状的发生情况和相关影响因素。方法 2015年1月至6月,选择1990年1月至1994年12月在福建医科大学附属漳州市医院行手术治疗的尿道下裂患者,并按1∶1匹配同期年龄和心理健康的成年人。采用Zung氏抑郁自评量表和自制的心理调查表对纳入患者的抑郁情况进行调查,并对抑郁相关影响因素进行分析。结果共纳入80例经手术治疗的尿道下裂患者和80例健康对照。两组男性第二性征发育均正常,双侧睾丸发育正常,测定血清睾酮水平无明显异常,术后阴茎长度、粗细与对照组比较均无明显差异。尿道下裂患者抑郁症状发生率为45.0%,而对照组仅为6.3%,其差异有统计学意义(χ2=6.632,P=0.01)。多元逐步回归分析结果显示,阴茎和阴囊外观满意度(F=16.210 3,P=0.001)、性生活满意度(F=4.621 2,P=0.036)和性功能(F=4.103 2,P=0.043)是影响尿道下裂患者术后抑郁症状的独立危险因素。结论尿道下裂患者术后常发生抑郁症状,主要影响因素为阴茎和阴囊外观满意度、性生活满意度和性功能。
Objective To analyze the incidence of postoperative depression and its influencing factors in patients with hypospadias. Methods From January to June 2015, patients with hypospadias surgically treated in Zhangzhou Hospital Affiliated to Fujian Medical University from January 1990 to December 1994 were selected and matched to the age and mental health of adults . The Zung’s self-rating depression scale and self-made psychological questionnaire were used to investigate the depression status of the patients and the influencing factors of depression were analyzed. Results A total of 80 surgically treated patients with hypospadias and 80 healthy controls were enrolled. Male secondary sexual development in both groups were normal, bilateral testis normal development, serum testosterone levels were no significant abnormalities, penile length, thickness compared with the control group no significant difference. The incidence of depression was 45.0% in patients with hypospadias, compared with 6.3% in the control group (χ2 = 6.632, P = 0.01). Multiple stepwise regression analysis showed that the penis and scrotum appearance satisfaction (F = 16.210 3, P = 0.001), sexual life satisfaction (F = 4.621 2, P = 0.036) and sexual function (F = 4.103 2, P = 0.043 ) Is an independent risk factor for postoperative depression in patients with hypospadias. Conclusions Patients with hypospadias often have depressive symptoms after surgery. The main influencing factors are appearance satisfaction of the penis and scrotum, sexual life satisfaction and sexual function.