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目的了解类风湿关节炎患者血脂异常情况及日常生活作息行为,为有针对性开展健康教育,预防由于生活因素引起的血脂异常提供参考依据。方法选取住院治疗的类风湿关节炎(RA)患者53人,对其进行问卷调查、体格检查及血清总胆固醇(TC)、甘油三酯(TG)、高密度(HDL-C)和低密度脂蛋白胆固醇(LDL-C)检测。结果 RA患者超重比例为37.7%。不能每天吃早餐和睡眠质量差分别为15.1%和37.7%。住院前坚持每天户外活动者为50.9%。有近40%和72%的RA患者能经常摄入新鲜蔬菜和水果,经常摄入奶及其制品的比例为58.5%,但每周摄入1次及以上鱼或海产品的比例较少,为34%。53名RA患者以血清HDL-C异常者检出率最高,为32.1%。年龄大于50岁、中度以上疾病活动度及超重都可明显升高血清TG、TC和LDL-C水平;使用激素能降低RA血清HDL-C水平。结论 RA患者日常生活作息行为尤其饮食习惯存在许多问题,血脂异常检出率较高,指导RA患者科学合理的饮食及日常作息行为,保持适宜体重对预防和降低血脂异常有益。
Objective To understand the dyslipidemia and routine behavior of patients with rheumatoid arthritis and to provide reference for health education and prevention of dyslipidemia caused by life factors. Methods Fifty-three patients with rheumatoid arthritis (RA) were enrolled in this study. They were investigated by questionnaires, physical examinations and serum total cholesterol (TC), triglyceride (TG), high density (HDL-C) Protein cholesterol (LDL-C) test. Results RA patients overweight ratio was 37.7%. Can not eat breakfast every day and poor quality of sleep were 15.1% and 37.7% respectively. 50.9% of people who hold daily outdoor activities before hospitalization. Nearly 40% of patients with RA and 72% of patients with RA regularly consume fresh vegetables and fruits. The proportion of regular intake of milk and its products is 58.5%, but the proportion of fish and seafood taken once or more per week is less, 34%. Fifty-three RA patients had the highest detection rate of serum HDL-C abnormality, accounting for 32.1%. Over 50 years of age, moderate and severe disease activity and overweight can significantly increase serum TG, TC and LDL-C levels; the use of hormones can reduce RA serum HDL-C levels. Conclusion There are many problems in daily life and work-related behaviors, especially eating habit in patients with RA. The detection rate of dyslipidemia is higher in patients with RA. It is helpful to guide patients with RA in scientific and reasonable diet and daily routine behaviors and maintain proper body weight to prevent and reduce dyslipidemia.